CD43 antibody (full length)

Catalog No. ABIN7879028

This Mouse Monoclonal antibody specifically detects CD43 in FACS, WB, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD43 antibody (full length) (ABIN7879028)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD43 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CDLA43-2

Product Details anti-CD43 Antibody

Binding Specificity: full length

Purpose: CD43 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD43 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD43 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background: CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt]

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity