CD43 antibody (full length)

Catalog No. ABIN7879029

The Mouse Monoclonal anti-CD43 antibody is suitable to detect CD43 in samples from Human. It has been validated for IHC (p).

Quick Overview for CD43 antibody (full length) (ABIN7879029)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD43 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDLA43-2

Product Details anti-CD43 Antibody

Binding Specificity: full length

Purpose: CD43 Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human SPN protein was used as the immunogen for the CD43 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD43 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD43 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: CD43

Background: CD43 is one of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). [UniProt]

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity