TNC antibody (full length)

Catalog No. ABIN7879135

The Mouse Monoclonal anti-TNC antibody (Clone TNC-4805) (ABIN7879135) specifically detects TNC in IHC (p). The antibody is reactive with Human samples.

Quick Overview for TNC antibody (full length) (ABIN7879135)

Target: TNC (Tenascin C (TNC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNC antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: TNC-4805

Product Details anti-TNC Antibody

Binding Specificity: full length

Purpose: Tenascin Antibody / TNC (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant human full-length protein was used as the immunogen for the Tenascin C antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Tenascin C antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Tenascin C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TNC

Target: TNC (Tenascin C (TNC))

Alternative Name: Tenascin

Background: In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of as Tenascin or Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

UniProt: P24821

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development