Tumor Protein p73 antibody (full length)

Catalog No. ABIN7879266

The Mouse Monoclonal anti-Tumor Protein p73 antibody is suitable to detect Tumor Protein p73 in samples from Human. It has been validated for IHC (p).

Quick Overview for Tumor Protein p73 antibody (full length) (ABIN7879266)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: P73-2531

Product Details anti-Tumor Protein p73 Antibody

Binding Specificity: full length

Purpose: p73 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human protein was used as the immunogen for this p73 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the p73 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: p73

Background: The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus