ZNF408 antibody (full length)

Catalog No. ABIN7879353

The Mouse Monoclonal anti-ZNF408 antibody is suitable to detect ZNF408 in samples from Human. It has been validated for WB and FACS.

Quick Overview for ZNF408 antibody (full length) (ABIN7879353)

Target: ZNF408 (Zinc Finger Protein 408 (ZNF408))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZNF408 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-ZNF408-1E5

Product Details anti-ZNF408 Antibody

Binding Specificity: full length

Purpose: ZNF408 Antibody / PRDM17 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human ZNF408 protein was used as the immunogen for the ZNF408 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the ZNF408 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the ZNF408 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ZNF408

Target: ZNF408 (Zinc Finger Protein 408 (ZNF408))

Alternative Name: ZNF408

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

UniProt: Q9H9D4