FGG antibody (N-Term)

Catalog No. ABIN7879601

This Mouse Monoclonal antibody specifically detects FGG in WB and IF. It exhibits reactivity toward Human.

Quick Overview for FGG antibody (N-Term) (ABIN7879601)

Target: FGG (Fibrinogen gamma Chain (FGG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGG antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 5H9

Product Details anti-FGG Antibody

Binding Specificity: N-Term

Purpose: FGG Antibody / Fibrinogen gamma chain / FIBG

Sequence: IRYLQEIYNS NNQKIVNLKE KVAQLEAQCQ E

Purification: Antigen affinity purified

Immunogen: N-terminal region amino acids IRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE from the human protein were used as the immunogen for the FGG antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the FGG antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FGG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Alternative Name: FGG

Background: Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

UniProt: P02679