HMGCR antibody

Catalog No. ABIN7879849

The Rabbit Monoclonal anti-HMGCR antibody (Clone AOCC-8) (ABIN7879849) specifically detects HMGCR in WB. The antibody is reactive with Human samples.

Quick Overview for HMGCR antibody (ABIN7879849)

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HMGCR antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AOCC-8

Product Details anti-HMGCR Antibody

Purpose: HMGCR Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Hmg Coa Reductase / HMGCR was used as the immunogen for the HMGCR antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HMGCR antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the HMGCR antibody at -20oC.

Target Details for HMGCR

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: HMGCR

Background: 3-hydroxy-3-methylglutaryl-coenzyme A reductase' is a transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha