ACSL4 antibody

Catalog No. ABIN7879892

This Mouse Monoclonal antibody specifically detects ACSL4 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ACSL4 antibody (ABIN7879892)

Target: ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACSL4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4I7

Product Details anti-ACSL4 Antibody

Purpose: ACSL4 Antibody / FACL4

Sequence: EPWTPETGLV TDAFKLKRKE LR

Purification: Affinity purified

Immunogen: Amino acids EPWTPETGLVTDAFKLKRKELR from the human protein were used as the immunogen for the ACSL4 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the ACSL4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ACSL4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ACSL4

Target: ACSL4 (Acyl-CoA Synthetase Long-Chain Family Member 4 (ACSL4))

Alternative Name: ACSL4

Background: Long-chain-fatty-acid--CoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. It is mapped to Xq23. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants.

UniProt: O60488