PRAS40 antibody

Catalog No. ABIN7879913

This Rabbit Monoclonal antibody specifically detects PRAS40 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRAS40 antibody (ABIN7879913)

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRAS40 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: ACHD-1

Product Details anti-PRAS40 Antibody

Purpose: PRAS40 Antibody / AKT1S1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human AKT1S1 / PRAS40 was used as the immunogen for the PRAS40 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PRAS40 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the PRAS40 antibody at -20oC.

Target Details for PRAS40

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Alternative Name: PRAS40

Background: PRAS40/AKT1S1 is a substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. It may also play a role in nerve growth factor-mediated neuroprotection. [UniProt]

UniProt: Q96B36

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect