APAF1 antibody

Catalog No. ABIN7879992

The Rabbit Monoclonal anti-APAF1 antibody is suitable to detect APAF1 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for APAF1 antibody (ABIN7879992)

Target: APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This APAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BHF-1

Product Details anti-APAF1 Antibody

Purpose: APAF1 Antibody / Apoptotic protease-activating factor 1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Apoptotic Peptidase Activating Factor 1 was used as the immunogen for the APAF1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the APAF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the APAF1 antibody at -20oC.

Target Details for APAF1

Target: APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))

Alternative Name: APAF1

Background: Apoptotic Peptidase Activating Factor 1 is a cytoplasmic protein that initiates apoptosis. And it is an essential downstream effector of p53-mediated apoptosis.

UniProt: O14727

Pathways: p53 Signaling, Apoptosis, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity