ALOX5 antibody

Catalog No. ABIN7879995

The Rabbit Monoclonal anti-ALOX5 antibody is suitable to detect ALOX5 in samples from Human. It has been validated for WB.

Quick Overview for ALOX5 antibody (ABIN7879995)

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ALOX5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AECE-1

Product Details anti-ALOX5 Antibody

Purpose: 5-Lipoxygenase Antibody / ALOX5

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human 5-Lipoxygenase / ALOX5 was used as the immunogen for the 5-Lipoxygenase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the 5-Lipoxygenase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the 5-Lipoxygenase antibody at -20oC.

Target Details for ALOX5

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Alternative Name: 5-Lipoxygenase

Background: The ALOX5 gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. [RefSeq]

UniProt: P09917