Recombinant ATRIP antibody

Catalog No. ABIN7880026

The Rabbit Monoclonal anti-ATRIP antibody (Clone 26A07) (ABIN7880026) specifically detects ATRIP in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant ATRIP antibody (ABIN7880026)

Target: ATRIP (ATR Interacting Protein (ATRIP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ATRIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 26A07

Product Details anti-ATRIP Antibody

Purpose: ATRIP Antibody / ATR-interacting protein

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to ATR-interacting protein was used as the immunogen for the ATRIP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ATRIP antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ATRIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATRIP

Target: ATRIP (ATR Interacting Protein (ATRIP))

Alternative Name: ATRIP

Background: ATR-interacting protein (ATRIP) is a key regulator of the DNA damage response, functioning as an essential partner of the ATR kinase. ATRIP binds to replication protein A-coated single-stranded DNA and recruits ATR to sites of DNA damage or replication stress, initiating checkpoint signaling that maintains genome stability.

ATRIP plays a vital role in coordinating cell cycle arrest and DNA repair processes in response to genotoxic stress. Defects in ATRIP function can compromise DNA damage checkpoint activation, leading to genomic instability and contributing to developmental abnormalities and disease susceptibility.

Using a high-quality ATRIP antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunoprecipitation. An ATRIP antibody from NSJ Bioreagents ensures consistent and reproducible results for studies in DNA repair, replication stress, and checkpoint signaling. Selecting the right ATRIP antibody is critical for advancing research in genome maintenance and disease mechanisms.

UniProt: Q8WXE1