ATG4A antibody

Catalog No. ABIN7880030

This Rabbit Polyclonal antibody specifically detects ATG4A in WB, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for ATG4A antibody (ABIN7880030)

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-ATG4A Antibody

Purpose: ATG4A Antibody

Sequence: LSKYEDQITI FTDYLEEYPD

Purification: Affinity purified

Immunogen: Amino acids LSKYEDQITIFTDYLEEYPD from the human protein were used as the immunogen for the ATG4A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ATG4A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ATG4A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Alternative Name: ATG4A

Background: Cysteine protease ATG4A is an enzyme that in humans is encoded by the ATG4A gene. It is mapped to Xq22.3. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.

UniProt: Q8WYN0

Pathways: Autophagy