Survivin antibody

Catalog No. ABIN7880050

The Rabbit Monoclonal anti-Survivin antibody (Clone DGD-2) (ABIN7880050) specifically detects Survivin in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for Survivin antibody (ABIN7880050)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DGD-2

Product Details anti-Survivin Antibody

Purpose: Survivin Antibody / BIRC5

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Survivin / Birc5 was used as the immunogen for the Survivin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Survivin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Survivin antibody at -20oC.

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: Survivin

Background: The BIRC5 gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. [RefSeq]

UniProt: O70201

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding