Survivin antibody

Catalog No. ABIN7880051

This Rabbit Monoclonal antibody specifically detects Survivin in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Survivin antibody (ABIN7880051)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Survivin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ABB-2

Product Details anti-Survivin Antibody

Purpose: BIRC5 Antibody / Survivin

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Survivin / BIRC5 was used as the immunogen for the BIRC5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BIRC5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the BIRC5 antibody at -20oC.

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: BIRC5

Background: The BIRC5 gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. [RefSeq]

UniProt: O15392

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding