BCAM antibody

Catalog No. ABIN7880052

The Rabbit Polyclonal anti-BCAM antibody is suitable to detect BCAM in samples from Human, Mouse and Rat. It has been validated for WB, FACS, IF and IHC (p).

Quick Overview for BCAM antibody (ABIN7880052)

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BCAM Antibody

Purpose: BCAM Antibody / CD239

Sequence: LLSLTSTLYL RLRKDDRDAS FHCAAHYSLP EGRH

Purification: Affinity purified

Immunogen: Amino acids LLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRH from the human protein were used as the immunogen for the BCAM antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BCAM antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the BCAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Alternative Name: BCAM

Background: Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene. It is mapped to 19q13.32. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P50895