Recombinant CDX2 antibody

Catalog No. ABIN7880212

The Mouse Monoclonal anti-CDX2 antibody (Clone rCDX2-6921) (ABIN7880212) specifically detects CDX2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant CDX2 antibody (ABIN7880212)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCDX2-6921

Product Details anti-CDX2 Antibody

Purpose: Recombinant Caudal Type Homeobox 2 Antibody / CDX2

Purification: Protein A/G affinity

Immunogen: A synthetic peptide from human CDX2 protein was used as the immunogen for the recombinant Caudal Type Homeobox 2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Caudal Type Homeobox 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Caudal Type Homeobox 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: Caudal Type Homeobox 2

Background: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance