Recombinant CDX2 antibody

Catalog No. ABIN7880214

The Rabbit Monoclonal anti-CDX2 antibody is suitable to detect CDX2 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CDX2 antibody (ABIN7880214)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDX2-4394R

Product Details anti-CDX2 Antibody

Purpose: Recombinant CDX2 Antibody

Purification: Protein A affinity chromatography

Immunogen: A recombinant protein fragment from the human protein was used as the immunogen for the recombinant CDX2 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant CDX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant CDX2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: CDX2

Background: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance