CEBPZ antibody

Catalog No. ABIN7880220

The Mouse Monoclonal anti-CEBPZ antibody is suitable to detect CEBPZ in samples from Human. It has been validated for FACS and IHC (p).

Quick Overview for CEBPZ antibody (ABIN7880220)

Target: CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEBPZ antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PCRP-CEBPZ-2D8

Product Details anti-CEBPZ Antibody

Purpose: CEBPZ Antibody

Purification: Protein A/G affinity

Immunogen: The protein domain of CEBPZ protein was used as the immunogen for the CEBPZ antibody.

Isotype: IgG2c

Application Details

Application Notes: Optimal dilution of the CEBPZ antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CEBPZ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CEBPZ

Target: CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))

Alternative Name: CEBPZ

Background: C/EBPZ (CCAAT/enhancer-binding protein Z), also known as CBF, CBF2, NOC1 or HSP-CBF is a 1,054 amino acid nuclear protein belonging to the CBF/MAK21 family. C/EBPZ stimulates transcription from the HSP70 and HSP40 promoters in a NF-Y dependent manner, requiring an intact NF-Y trimer which binds to the DNA. C/EBPZ is thought to be a potential tumor suppressor gene, and aberrant methylation of the C/EBPZ promoter may be involved with acute myeloid leukemia. The C/EBPZ gene is conserved in a wide number of species including chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish and C. elegans and is located on human chromosome 2. Chromosome 2, the second largest human chromosome, consists of 237 million bases encoding over 1,400 genes, comprising approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2.

UniProt: Q03701