CD45RB antibody

Catalog No. ABIN7880315

This Rabbit Polyclonal antibody specifically detects CD45RB in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD45RB antibody (ABIN7880315)

Target: CD45RB

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD45RB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD45RB Antibody

Purpose: CD45RB Antibody

Purification: Protein A affinity chromatography

Immunogen: Human CD45RB protein was used as the immunogen for the CD45RB antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CD45RB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD45RB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD45RB

Target: CD45RB

Alternative Name: CD45RB

Background: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.

UniProt: P08575