CD6 antibody

Catalog No. ABIN7880334

The Mouse Monoclonal anti-CD6 antibody is suitable to detect CD6 in samples from Human. It has been validated for IHC (p).

Quick Overview for CD6 antibody (ABIN7880334)

Target: CD6

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM547

Product Details anti-CD6 Antibody

Purpose: Anti-CD6 Antibody

Purification: Protein G affinity chromatography

Immunogen: Human recombinant protein was used as the immunogen for this anti-CD6 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The optimal dilution of the anti-CD6 antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the anti-CD6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD6

Target: CD6

Alternative Name: CD6

Background: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular 'scavenger receptor cysteine-rich' (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

UniProt: P30203