CD8B antibody

Catalog No. ABIN7880365

The Rat Monoclonal anti-CD8B antibody (Clone H35-17-2) (ABIN7880365) specifically detects CD8B in FACS, Func and IF. The antibody is reactive with Mouse samples.

Quick Overview for CD8B antibody (ABIN7880365)

Target: CD8B (CD8b Molecule (CD8B))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD8B antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)

Clone: H35-17-2

Product Details anti-CD8B Antibody

Purpose: CD8b Antibody

Purification: Protein G affinity chromatography

Immunogen: Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CD8b antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD8b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD8B

Target: CD8B (CD8b Molecule (CD8B))

Alternative Name: CD8b

Background: This monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.

UniProt: P10300

Pathways: TCR Signaling