CHD4 antibody

Catalog No. ABIN7880419

The Mouse Monoclonal anti-CHD4 antibody (Clone 3F2-4) (ABIN7880419) specifically detects CHD4 in WB, IF, ELISA and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for CHD4 antibody (ABIN7880419)

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3F2-4

Product Details anti-CHD4 Antibody

Purpose: CHD4 Antibody / Chromodomain helicase DNA binding protein 4

Sequence: ASGLGSPSPC SAGSEEEDM

Purification: Protein G affinity chromatography

Immunogen: Amino acids ASGLGSPSPCSAGSEEEDM and CSRLANRAPEPPPQQVAQQQ were used as the immunogen for the CHD4 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CHD4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CHD4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CHD4

Target: CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

Alternative Name: CHD4

Background: CHD4/Mi-2b is a component of the nucleosome remodeling and deacetylase (NuRD) complex which is a multi-subunit protein complex containing both histone deacetylase and nucleosome-dependent ATPase subunits. Current models predict that this complex function primarily in transcriptional repression. Accumulating evidence indicates that NuRD may regulate the transcription of specific genes by interacting with specific transcriptional factors. In addition, the NuRD complex may also participate in genome-wide transcriptional regulation through an association with histone tails.

UniProt: Q14839