Tissue factor antibody

Catalog No. ABIN7880460

The Rabbit Monoclonal anti-Tissue factor antibody is suitable to detect Tissue factor in samples from Human. It has been validated for WB.

Quick Overview for Tissue factor antibody (ABIN7880460)

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Tissue factor antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GGE-6

Product Details anti-Tissue factor Antibody

Purpose: Tissue Factor Antibody / CD142

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Tissue Factor / F3 was used as the immunogen for the Tissue Factor antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Tissue Factor antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Tissue Factor antibody at -20oC.

Target Details for Tissue factor

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Alternative Name: Tissue Factor

Background: The F3 gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. [RefSeq]

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling