C3 antibody

Catalog No. ABIN7880494

The Rabbit Monoclonal anti-C3 antibody (Clone AEIC-3) (ABIN7880494) specifically detects C3 in WB. The antibody is reactive with Human samples.

Quick Overview for C3 antibody (ABIN7880494)

Target: C3 (Complement Component 3 (C3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This C3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AEIC-3

Product Details anti-C3 Antibody

Purpose: Complement C3 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Complement C3 was used as the immunogen for the Complement C3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Complement C3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Complement C3 antibody at -20oC.

Target Details for C3

Target: C3 (Complement Component 3 (C3))

Alternative Name: Complement C3

Background: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [RefSeq]

UniProt: P01024

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling