Dystrophin antibody

Catalog No. ABIN7880663

This Rabbit Monoclonal antibody specifically detects Dystrophin in WB. It exhibits reactivity toward Human.

Quick Overview for Dystrophin antibody (ABIN7880663)

Target: Dystrophin (DMD)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Dystrophin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AOGG-4

Product Details anti-Dystrophin Antibody

Purpose: Dystrophin Antibody / DMD

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Dystrophin / DMD was used as the immunogen for the Dystrophin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Dystrophin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Dystrophin antibody at -20oC.

Target Details for Dystrophin

Target: Dystrophin (DMD)

Alternative Name: Dystrophin

Background: The DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development