CD15 antibody

Catalog No. ABIN7880828

This Mouse Monoclonal antibody specifically detects CD15 in FACS, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD15 antibody (ABIN7880828)

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD15 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM119

Product Details anti-CD15 Antibody

Purpose: CD15 Antibody / SSEA-1

Purification: PEG precipitation

Immunogen: Human U937 cells were used as the immunogen for the CD15 antibody.

Isotype: IgM, kappa

Application Details

Application Notes: Optimal dilution of the CD15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD15 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD15

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Alternative Name: CD15

Background: CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on 95 % of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

UniProt: P22083