CD15 antibody (AA 199-302)

Catalog No. ABIN1724873

There are 2+ publications for this product available. The Mouse Monoclonal anti-CD15 antibody is suitable to detect CD15 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CD15 antibody (AA 199-302) (ABIN1724873)

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6B11B4

Product Details anti-CD15 Antibody

Binding Specificity: AA 199-302

Purpose: FUT4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FUT4 (AA: 199-302) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD15 antibody (ABIN1724873)

Sabry, Tsirogianni, Bakhsh, North, Sivakumaran, Giannopoulos, Anderson, Mackinnon, Lowdell: "Leukemic priming of resting NK cells is killer Ig-like receptor independent but requires CD15-mediated CD2 ligation and natural cytotoxicity receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 12, pp. 6227-34, (2011) (PubMed).

de Antonellis, Medaglia, Cusanelli, Andolfo, Liguori, De Vita, Carotenuto, Bello, Formiggini, Galeone, De Rosa, Virgilio, Scognamiglio, Sciro, Basso, Schulte, Cinalli, Iolascon, Zollo: "MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma." in: PLoS ONE, Vol. 6, Issue 9, pp. e24584, (2011) (PubMed).

Target Details for CD15

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Alternative Name: FUT4

Background: The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).

Molecular Weight: 59 kDa

Gene ID: 2526

UniProt: P22083