FUS antibody

Catalog No. ABIN7880833

The Rabbit Polyclonal anti-FUS antibody (ABIN7880833) specifically detects FUS in WB, IF, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FUS antibody (ABIN7880833)

Target: FUS (Fused in Sarcoma (FUS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FUS Antibody

Purpose: TLS Antibody / Translocated in liposarcoma protein / FUS

Sequence: ENVTIESVAD YFKQ

Purification: Antigen affinity purified

Immunogen: Amino acids ENVTIESVADYFKQ from the human protein were used as the immunogen for the TLS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TLS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TLS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: TLS

Background: RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

UniProt: P35637