GLA antibody

Catalog No. ABIN7880847

The Rabbit Polyclonal anti-GLA antibody is suitable to detect GLA in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for GLA antibody (ABIN7880847)

Target: GLA (Galactosidase, alpha (GLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GLA Antibody

Purpose: Galactosidase alpha Antibody / Gla

Sequence: KRKLGFYEWT SRLRSHIN

Purification: Affinity purified

Immunogen: Amino acids KRKLGFYEWTSRLRSHIN from the human protein were used as the immunogen for the Galactosidase alpha antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Galactosidase alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Galactosidase alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GLA

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: Galactosidase alpha

Background: Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interactome