Recombinant GLB1 antibody

Catalog No. ABIN7880848

The Rabbit Monoclonal anti-GLB1 antibody (Clone 25G11) (ABIN7880848) specifically detects GLB1 in IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant GLB1 antibody (ABIN7880848)

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GLB1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 25G11

Product Details anti-GLB1 Antibody

Purpose: GLB1 Antibody / Beta galactosidase

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Beta galactosidase protein was used as the immunogen for the GLB1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GLB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GLB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GLB1

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Alternative Name: GLB1

Background: GLB1 (Beta-galactosidase) is a lysosomal hydrolase that catalyzes the breakdown of terminal beta-galactosides into monosaccharides. This enzyme is critical for the proper degradation of glycolipids, glycoproteins, and glycosaminoglycans. Researchers commonly use a GLB1 antibody to study lysosomal function and carbohydrate metabolism.

Deficiency of GLB1 activity is associated with lysosomal storage disorders such as GM1 gangliosidosis and Morquio B disease. These conditions highlight the importance of GLB1 in cellular homeostasis and human health. Employing a GLB1 antibody enables detection of protein expression and activity in both normal physiology and disease contexts.

NSJ Bioreagents provides a high-quality GLB1 antibody validated for applications including western blot, immunohistochemistry, and immunofluorescence. Using a GLB1 antibody ensures sensitive and reproducible results for studies of lysosomal biology, enzymatic function, and inherited metabolic disorders.

UniProt: P16278

Pathways: Glycosaminoglycan Metabolic Process