HCAM antibody

Catalog No. ABIN7880959

The Mouse Monoclonal anti-HCAM antibody (Clone 7H7) (ABIN7880959) specifically detects HCAM in WB, FACS and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for HCAM antibody (ABIN7880959)

Target: HCAM

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 7H7

Product Details

Purpose: HCAM Antibody / CD44

Sequence: RFAGVFHVEK NGRYSISRTE AADLCKAF

Purification: Affinity purified

Immunogen: Amino acids RFAGVFHVEKNGRYSISRTEAADLCKAF from the human protein were used as the immunogen for the HCAM antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the HCAM antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HCAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details

Target: HCAM

Background: CD44 is also known as HCAM, LHR and MC56. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

UniProt: P16070