Histone H2A antibody

Catalog No. ABIN7881071

This Rabbit Monoclonal antibody specifically detects Histone H2A in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for Histone H2A antibody (ABIN7881071)

Target: Histone H2A

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DED-8

Product Details anti-Histone H2A Antibody

Purpose: Hydroxyl-Histone H2A Antibody (Tyr39)

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Histone H2A (surrounding hydroxylated tyrosine 39) was used as the immunogen for the hydroxyl-Histone H2A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the hydroxyl-Histone H2A antibody (Tyr39) should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the hydroxyl-Histone H2A antibody (Tyr39) at -20oC.

Target Details for Histone H2A

Target: Histone H2A

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]

UniProt: P04908