IGF2BP3 antibody

Catalog No. ABIN7881187

The Rabbit Monoclonal anti-IGF2BP3 antibody (Clone AEDB-9) (ABIN7881187) specifically detects IGF2BP3 in WB. The antibody is reactive with Human samples.

Quick Overview for IGF2BP3 antibody (ABIN7881187)

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IGF2BP3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AEDB-9

Product Details anti-IGF2BP3 Antibody

Purpose: IGF2BP3 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Insulin-like growth factor 2 mRNA-binding protein 3 was used as the immunogen for the IGF2BP3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IGF2BP3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the IGF2BP3 antibody at -20oC.

Target Details for IGF2BP3

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Alternative Name: IGF2BP3

Background: RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. [UniProt]

UniProt: O00425