ICAM-3/CD50 antibody

Catalog No. ABIN7881229

The Mouse Monoclonal anti-ICAM-3/CD50 antibody (Clone CG106) (ABIN7881229) specifically detects ICAM-3/CD50 in FACS, IF and BP. The antibody is reactive with Human samples.

Quick Overview for ICAM-3/CD50 antibody (ABIN7881229)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM-3/CD50 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Peptide (BP)

Clone: CG106

Product Details anti-ICAM-3/CD50 Antibody

Purpose: CD50 Antibody / ICAM-3

Purification: Protein G affinity chromatography

Immunogen: Stimulated human leukocytes were used as the immunogen for the CD50 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CD50 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD50 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: CD50

Background: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.

UniProt: P32942