IL-25 antibody

Catalog No. ABIN7881299

The Mouse Monoclonal anti-IL-25 antibody (Clone IL25-625) (ABIN7881299) specifically detects IL-25 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for IL-25 antibody (ABIN7881299)

Target: IL-25 (IL25) (Interleukin 25 (IL25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-25 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL25-625

Product Details anti-IL-25 Antibody

Purpose: IL-25 Antibody / IL-17E

Purification: Protein A/G affinity

Immunogen: A recombinant protein fragment was used as the immunogen for the IL-25 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the IL-25 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IL-25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IL-25

Target: IL-25 (IL25) (Interleukin 25 (IL25))

Alternative Name: IL-25

Background: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.

UniProt: Q9H293