Recombinant IL7R antibody

Catalog No. ABIN7881317

The Rabbit Monoclonal anti-IL7R antibody (Clone 22I71) (ABIN7881317) specifically detects IL7R in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant IL7R antibody (ABIN7881317)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 22I71

Product Details anti-IL7R Antibody

Purpose: IL7RA Antibody / Interleukin-7 receptor alpha / CD127

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Interleukin-7 receptor alpha was used as the immunogen for the IL7RA antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IL7RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IL7RA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: IL7RA

Background: Interleukin-7 receptor alpha (IL7RA) is a type I transmembrane glycoprotein that forms part of the receptor complex for interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP). It plays a crucial role in lymphocyte development, survival, and homeostasis, particularly in T-cell and B-cell biology.

Genetic variations in IL7RA have been associated with susceptibility to autoimmune diseases, such as multiple sclerosis and type 1 diabetes, as well as immune deficiency disorders. IL7RA signaling regulates lymphocyte proliferation, differentiation, and maintenance, making it a valuable focus for immunological and therapeutic research.

Using a high-quality IL7RA antibody enables accurate detection of the protein in applications including western blot, immunohistochemistry, and flow cytometry. An IL7RA antibody from NSJ Bioreagents delivers consistent and reproducible performance for studies on immune signaling, lymphocyte biology, and disease pathogenesis. Selecting the right IL7RA antibody ensures reliable results in both basic research and clinical investigations.

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size