Recombinant Iba1 antibody

Catalog No. ABIN7881325

The Rabbit Monoclonal anti-Iba1 antibody is suitable to detect Iba1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Recombinant Iba1 antibody (ABIN7881325)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Iba1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AFGH-1

Product Details anti-Iba1 Antibody

Purpose: AIF-1 Antibody / Allograft inflammatory factor 1 / IBA1

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to Allograft inflammatory factor 1 was used as the immunogen for the AIF-1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AIF-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the AIF-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Iba1

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: AIF-1

Background: Allograft inflammatory factor 1 (AIF-1) is a cytoplasmic, calcium-binding protein predominantly expressed in activated macrophages and microglia. It is involved in the regulation of immune and inflammatory responses, contributing to cell proliferation, migration, and cytokine production. AIF-1 plays roles in vascular pathology, tissue repair, and immune-mediated diseases.

Elevated expression of AIF-1 has been associated with various pathological conditions, including atherosclerosis, autoimmune disorders, and neuroinflammation. It serves as a marker for activated immune cells, making it valuable for studying inflammation-related mechanisms and disease progression.

Using a high-quality AIF-1 antibody allows sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An AIF-1 antibody from NSJ Bioreagents provides reliable performance for research in immunology, neurobiology, and cardiovascular disease. Selecting the right AIF-1 antibody ensures accurate and reproducible experimental outcomes.

UniProt: P55008

Pathways: Smooth Muscle Cell Migration