NECAB1 antibody

Catalog No. ABIN7881752

The Mouse Monoclonal anti-NECAB1 antibody (Clone NECAB1-7680) (ABIN7881752) specifically detects NECAB1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for NECAB1 antibody (ABIN7881752)

Target: NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NECAB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: NECAB1-7680

Product Details anti-NECAB1 Antibody

Purpose: NECAB1 Antibody / N-terminal EF-hand calcium binding protein 1

Purification: Protein A/G affinity

Immunogen: Recombinant human NECAB1 protein was used as the immunogen for the NECAB1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NECAB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NECAB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NECAB1

Target: NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))

Alternative Name: NECAB1

Background: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP1 (N-terminal EF-hand calcium binding protein 1), also known as STIP-1 or neuronal calcium-binding protein 1 (NECAB1), is a 351 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and 2 EF-hand domains. Expressed in brain, EF-CBP1 interacts with copine 6 and Syntaxin, and exists as two alternatively spliced isoforms. The gene encoding EF-CBP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

UniProt: Q8N987