NME1 antibody
Quick Overview for NME1 antibody (ABIN7881819)
Target
See all NME1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- NME1 Antibody / NM23A
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Purification
- Affinity purified
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Immunogen
- A synthetic peptide specific to human NM23A / NME1 was used as the immunogen for the NME1 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the NME1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store the NME1 antibody at -20oC.
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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Alternative Name
- NME1
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Background
- This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [RefSeq]
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UniProt
- P15531
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Pathways
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
Target
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