Recombinant PHOX2B antibody

Catalog No. ABIN7881894

This Rabbit Monoclonal antibody specifically detects PHOX2B in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant PHOX2B antibody (ABIN7881894)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PHOX2B-7792R

Product Details anti-PHOX2B Antibody

Purpose: Paired-like homeobox 2B Antibody / PHOX2B

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human protein was used as the immunogen for the Paired-like homeobox 2B antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Paired-like homeobox 2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Paired-like homeobox 2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: Paired-like homeobox 2B

Background: Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for the formation of autonomic ganglia in the autonomic nervous system. PHOX2B is expressed in neuroblastoma, brain and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2).

UniProt: Q99453