Recombinant PHF8 antibody

Catalog No. ABIN7881921

This Rabbit Monoclonal antibody specifically detects PHF8 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Recombinant PHF8 antibody (ABIN7881921)

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PHF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ADAI-16

Product Details anti-PHF8 Antibody

Purpose: PHF8 Antibody / PHD finger protein 8

Purification: Affinity chromatography

Immunogen: A peptide sequence specific to PHD finger protein 8 protein was used as the immunogen for the PHF8 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PHF8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PHF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PHF8

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Alternative Name: PHF8

Background: PHD finger protein 8 (PHF8) is a histone demethylase that specifically removes methyl groups from lysine residues on histone H3, including H3K9me2 and H3K27me2. By altering chromatin structure, PHF8 regulates transcriptional activation and repression, influencing processes such as cell cycle progression, neuronal development, and differentiation.

PHF8 contains a PHD finger domain that recognizes specific histone modifications, allowing it to target distinct genomic loci. Mutations in PHF8 have been associated with X-linked intellectual disability and craniofacial anomalies. Research on PHF8 provides valuable insights into epigenetic regulation, development, and disease mechanisms.

Using a high-quality PHF8 antibody enables precise detection in applications such as western blot, immunohistochemistry, and chromatin immunoprecipitation. A PHF8 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in epigenetics, transcriptional regulation, and developmental biology. Selecting the right PHF8 antibody is essential for generating consistent and meaningful results.

UniProt: Q9UPP1