Podoplanin antibody

Catalog No. ABIN7881984

This Mouse Monoclonal antibody specifically detects Podoplanin in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Podoplanin antibody (ABIN7881984)

Target: Podoplanin (PDPN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: D2-40

Product Details anti-Podoplanin Antibody

Purpose: Podoplanin Antibody (azide and preservative free)

Purification: Protein G affinity

Immunogen: Resected tissue from dysgeminoma of the ovary was used as the immunogen for the Podoplanin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Podoplanin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background: Podoplanin is a transmembrane mucoprotein (38 kDa) recognized by the D2-40 monoclonal antibody. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells. Podoplanin is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi’s Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport