Recombinant Podoplanin antibody

Catalog No. ABIN7881986

The Rabbit Monoclonal anti-Podoplanin antibody (Clone PDPN-8950R) (ABIN7881986) specifically detects Podoplanin in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Podoplanin antibody (ABIN7881986)

Target: Podoplanin (PDPN)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: PDPN-8950R

Product Details anti-Podoplanin Antibody

Purpose: Podoplanin Antibody / PA2.26 antigen / Gp36 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human PDPN protein was used as the immunogen for the Podoplanin antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Podoplanin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport