Recombinant Podoplanin antibody

Catalog No. ABIN7881987

This Rabbit Monoclonal antibody specifically detects Podoplanin in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Podoplanin antibody (ABIN7881987)

Target: Podoplanin (PDPN)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PDPN-8950R

Product Details anti-Podoplanin Antibody

Purpose: Podoplanin Antibody / PA2.26 antigen / Gp36

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human PDPN protein was used as the immunogen for the Podoplanin antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Podoplanin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport