Prolactin Receptor antibody

Catalog No. ABIN7882036

The Mouse Monoclonal anti-Prolactin Receptor antibody is suitable to detect Prolactin Receptor in samples from Human. It has been validated for IHC (p).

Quick Overview for Prolactin Receptor antibody (ABIN7882036)

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM213

Product Details anti-Prolactin Receptor Antibody

Purpose: Anti-Prolactin Receptor Antibody

Purification: Protein G affinity chromatography

Immunogen: Semi-purified human prolactin receptor was used as the immunogen for this anti-Prolactin Receptor antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The optimal dilution of the anti-Prolactin Receptor antibody for each application should be determined by the researcher.

1. Staining of formalin/paraffin tissues requires digestion of tissue sections with Pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37oC.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the anti-Prolactin Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: Prolactin Receptor

Background: It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus