The Mouse Monoclonal anti-PSMA5 antibody (Clone 426CT8-5-1) (ABIN7882070) specifically detects PSMA5 in WB, IHC (p) and IF.
The antibody is reactive with Human, Mouse and Rat samples.
The stated application concentrations are suggested starting points. Titration of the PSMA5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the PSMA5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
PSMA5
(Proteasome Subunit alpha 5 (PSMA5))
Alternative Name
PSMA5
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.