P2RY12 antibody

Catalog No. ABIN7882111

The Rabbit Polyclonal anti-P2RY12 antibody is suitable to detect P2RY12 in samples from Mouse and Rat. It has been validated for WB and FACS.

Quick Overview for P2RY12 antibody (ABIN7882111)

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY12 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-P2RY12 Antibody

Purpose: P2y12 Antibody / P2Y purinoceptor 12

Purification: Antigen affinity purified

Immunogen: Amio acids NRRPKDKDVTKCSFL were used as the immunogen for the P2y12 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the P2y12 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the P2y12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for P2RY12

Target: P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))

Alternative Name: P2y12

Background: P2Y12 is a chemoreceptor for adenosine diphosphate (ADP) that belongs to the Gi class of a group of G protein-coupled (GPCR) purinergic receptors. The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

UniProt: Q9CPV9