PKM2 antibody

Catalog No. ABIN7882118

The Rabbit Monoclonal anti-PKM2 antibody (Clone GCB-16) (ABIN7882118) specifically detects PKM2 in WB. The antibody is reactive with Human samples.

Quick Overview for PKM2 antibody (ABIN7882118)

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PKM2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GCB-16

Product Details anti-PKM2 Antibody

Purpose: PKM2 Antibody / Pyruvate Kinase

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human PKM2 was used as the immunogen for the PKM2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PKM2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the PKM2 antibody at -20oC.

Target Details for PKM2

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Alternative Name: PKM2

Background: The PKM gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [RefSeq]

UniProt: P14618

Pathways: Warburg Effect