Retinoic Acid Receptor beta antibody

Catalog No. ABIN7882159

The Rabbit Monoclonal anti-Retinoic Acid Receptor beta antibody is suitable to detect Retinoic Acid Receptor beta in samples from Human. It has been validated for WB.

Quick Overview for Retinoic Acid Receptor beta antibody (ABIN7882159)

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Retinoic Acid Receptor beta antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AEHH-18

Product Details anti-Retinoic Acid Receptor beta Antibody

Purpose: RARB Antibody / Retinoic Acid Receptor beta

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Retinoic Acid Receptor beta / RARB was used as the immunogen for the RARB antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RARB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the RARB antibody at -20oC.

Target Details for Retinoic Acid Receptor beta

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Alternative Name: RARB

Background: The RARB gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [RefSeq]

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway